Since its inception in World War II, the clinical trial has evolved into a standard procedure in determining therapeutic efficacy in many Western industrial democracies. Its features include a "control" group of patients that do not receive the experimental treatment, the random allocation of patients to either the experimental or control group, and the use of blind assessment so that the researchers do not know which patients are in either group. Even though it has been only within the past generation that the clinical trial has moved to the forefront of medical research, comparative statistics in a therapeutic context has a much longer history. From that history J. Rosser Matthews chooses to discuss three crucial debates: that among clinicians before the Parisian Academy of Medicine in 1837, the debate in the German physiological literature during the 1850s, and, in the early twentieth century, the debate over the bacteriologist's diagnostic technique involving the "opsonic index." Matthews demonstrates that despite the very real differences separating clinician, physiologist, and bacteriologist, they all shared an antipathy toward the methods of the statistician. Since they viewed medical judgment as a form of "tacit knowledge," they downplayed the concerns of the medical statistician who was attempting to make medical inference into something explicit and quantitative. Only when "medical decision-making" moved from the cloistered confines of professional medical expertise into the arena of open political debate could the medical statistician (and the clinical trial) gain the upper hand.

Around 50,000 British people buy second homes abroad each year. Among the popular destinations are France, Spain, Italy and Portugal. This book on buying a property in Portugal has been written by someone who has already done it themselves. Use their experience to learn about the mistakes you can avoid. CONTENTS: 1. Why Portugal? 2. Where? 3. What to buy? 4. Finding property/making a start 5. Renting whilst you look 6. The people involved 7. The process 8. Buying timeshare/property to let 9. Renovating or building your own 10. Money matters 11. Before you go 12. Portuguese systems 13. Daily life 14. Enjoying life in Portugal 15. Changing your mind

Identity 2.0 is the follow-up title to the now sold-out Total Idetity book. Whereas the previous title showcased the projects of the design studio Total Identity , this new book takes a much broader perspective. From the viewpoint of identity, it looks at current and future issues that influence businesses, institutions and service-oriented organizations. The book connects identity - as the driving force behind innovation and change processes - to social and economic topics, illustrated with cases and the opinions of creative and business companies that have participated in projects with Total Identity or have an interesting view on those topics.

Is everything in a university for sale if the price is right? In this book, one of America's leading educators cautions that the answer is all too often "yes." Taking the first comprehensive look at the growing commercialization of our academic institutions, Derek Bok probes the efforts on campus to profit financially not only from athletics but increasingly, from education and research as well. He shows how such ventures are undermining core academic values and what universities can do to limit the damage. Commercialization has many causes, but it could never have grown to its present state had it not been for the recent, rapid growth of money-making opportunities in a more technologically complex, knowledge-based economy. A brave new world has now emerged in which university presidents, enterprising professors, and even administrative staff can all find seductive opportunities to turn specialized knowledge into profit. Bok argues that universities, faced with these temptations, are jeopardizing their fundamental mission in their eagerness to make money by agreeing to more and more compromises with basic academic values. He discusses the dangers posed by increased secrecy in corporate-funded research, for-profit Internet companies funded by venture capitalists, industry-subsidized educational programs for physicians, conflicts of interest in research on human subjects, and other questionable activities. While entrepreneurial universities may occasionally succeed in the short term, reasons Bok, only those institutions that vigorously uphold academic values, even at the cost of a few lucrative ventures, will win public trust and retain the respect of faculty and students. Candid, evenhanded, and eminently readable, Universities in the Marketplace will be widely debated by all those concerned with the future of higher education in America and beyond.

Interviews met ruim twintig Nederlandse leidinggevenden op het hoogste niveau uit het bedrijfsleven, de media, politiek, sport, zorg en nongouvernementele organisaties.

Hét antwoord op 'Dit kan niet waar zijn'. 0Persoonlijke drama's, knallende strijd, withete frustratie, ongekende euforie en gedrevenheid. Vanuit een anti-kraakkantoorpand in Amsterdam Sloterdijk wil een stel jonge honden de wereld veranderen. Hun doel: oprichting van de eerste onafhankelijke bank in decennia. Lukt het ze om met passie en nieuwe technologie een heel ander soort bank te beginnen? Eentje zonder risico's, die zijn geld louter verdient met steengoede diensten? Zou dat kunnen in Nederland, vóórdat de grote jongens in Amerika hen voor zijn? Elke dag weer is een achtbaanrit met onzekere uitkomst. "Met z'n allen wisten we op elk moment van de dag en nacht één ding zeker: hier gebeurt het. Het lukt of het lukt niet, maar het gebeurt hier wél!"

Neurologische visie op aankoopgedrag van consumenten en de rol van de hersenen daarbij.

Ervaringen en inzichten van de succesvolle Britse ondernemer, oprichter van de Virgin Group.

The ever tighter linking of our food, water, and energy systems in the context of a changing climate is leading to increasing turbulence in the world. As a consequence, it becomes ever more crucial to develop cities, regions, and economies with resilience in mind. Because of multinational corporations’ global reach, substantial resources, and information-driven leadership structures, these entities can play a major, constructive role in improving our understanding and design of resilient systems. This volume is the product of the Resilience Action Initiative, a collaboration among Dow, DuPont, IBM, McKinsey, Shell, Siemens, Swiss Re, Unilever, and Yara designed to explore possible corporate contributions to global resilience, especially at the nexus of water, food, and energy. Aggressively forward-thinking and consistent with an enlightened self-interest, the ideas considered here represent a corporate perspective on the broad collaborations required for a more resilient world.

"A practical guide to understanding and counteracting accounting fraud around the world. As businesses continue to expand globally into new and emerging markets, bribery and corruption risks have increased exponentially. The Accountant's Guide to Bribery and Corruption Risks offers a comprehensive look at this growing problem, and at the Foreign Corrupt Practices Act (FCPA) and other international anti-bribery and corruption conventions. Presenting hypothetical examples of situations companies will face, along with practical solutions, the book offers detailed global guidance on a region and country-specific basis.The FCPA prohibits US companies and their subsidiaries from bribing foreign officials, either directly or indirectly through intermediaries, for the purpose of obtaining or retaining business. It also requires companies to keep accurate records of all business transactions and maintain an effective system of internal accounting controls. Internationally, the Organization of Economic Cooperation and Development's (OECD's) anti-bribery convention has been adopted by 38 countries and creates legally binding standards related to bribery of foreign public officials.Written by renowned accounting fraud experts Jeffrey Taylor, Richard A. Sibery, and Brian P. Loughman, and providing an introduction and overview of the Foreign Corrupt Practices Act (FCPA) and international bribery laws, The Accountant's Guide considers: How to conduct FCPA risk assessments and investigations How to consider FCPA specific financial controls How to implement an FCPA compliance program and how to measure FCPA compliance The risk of bribery and corruption continues to be an area of concern for companies around the world, but armed with The Accountant's Guide to Bribery and Corruption Risks, it is easier than ever to understand the challenges that exist and how to deal with them"--

An international economic advisor shares a wide-spectrum theory about how to enable economic success throughout the world, posing solutions to top political, environmental, and social problems that contribute to poverty.

Readers will learn how to ride the business-to-business wave on the Internet in this unique cyber-primer, with advice on how to set up a decent site, market a successful e-business, and predict future trends in this hot market.

Helps readers sift through the thousands of websites and investmant opportunities on the Internet.